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Microcephaly family protein MCPH1 stabilizes RAD51 filaments
Microcephalin 1 (MCPH1) was identified from genetic mutations in patients with primary autosomal recessive microcephaly. In response to DNA double-strand breaks (DSBs), MCPH1 forms damage-induced foci and recruits BRCA2–RAD51 complex, a key component of the DSB repair machinery for homologous recomb...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7498314/ https://ncbi.nlm.nih.gov/pubmed/32735676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa636 |
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