Effects of Hypercapnia, an Element of Obstructive Respiratory Disorders on Pancreatic Cancer Chemoresistance and Progression

BACKGROUND: Chronic obstructive respiratory disorders (ORD) are linked to increased rates of cancer related deaths. Little is known about the effects of hypercapnia (elevated CO(2)) on pancreatic ductal adenocarcinoma (PDAC) development and drug-resistance. STUDY DESIGN: Two PDAC cell-lines were exp...

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Bibliografiske detaljer
Udgivet i:J Am Coll Surg
Main Authors: Nevler, Avinoam, Brown, Samantha Z, Nauheim, David, Portocarrero, Carla, Bassig, Jonathan, Schultz, Christopher W, McCarthy, Grace, Lavu, Harish, Yeo, Theresa P, Yeo, Charles J, Brody, Jonathan R
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498306/
https://ncbi.nlm.nih.gov/pubmed/32058016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2019.12.033
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