A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2

BACKGROUND: Variation in an individual’s genetic status can impact the development of pancreatic ductal adenocarcinoma; however, the m ajority of familial pancreatic cancers (FPC) cannot yet be attributed to a specific inherited mutation. We present data suggesting a correlation between loss-of-func...

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Detalhes bibliográficos
Publicado no:J Am Coll Surg
Main Authors: Nevler, Avinoam, Muller, Alexander J, Cozzitorto, Joseph A, Goetz, Austin, Winter, Jordan M, Yeo, Theresa P, Lavu, Harish, Yeo, Charles J, Prendergast, George C, Brody, Jonathan R
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047862/
https://ncbi.nlm.nih.gov/pubmed/29426021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2017.12.052
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