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Lack of RAC1 in macrophages protects against atherosclerosis

The Rho GTPase RAC1 is an important regulator of cytoskeletal dynamics, but the role of macrophage-specific RAC1 has not been explored during atherogenesis. We analyzed RAC1 expression in human carotid atherosclerotic plaques using immunofluorescence and found higher macrophage RAC1 expression in ad...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bandaru, Sashidar, Ala, Chandu, Ekstrand, Matias, Akula, Murali K., Pedrelli, Matteo, Liu, Xi, Bergström, Göran, Håversen, Liliana, Borén, Jan, Bergo, Martin O., Akyürek, Levent M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498073/
https://ncbi.nlm.nih.gov/pubmed/32941503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239284
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