Depletion of ATP and glucose in advanced human atherosclerotic plaques

OBJECTIVE: Severe hypoxia develops close to the necrotic core of advanced human atherosclerotic plaques, but the energy metabolic consequences of this hypoxia are not known. In animal models, plaque hypoxia is also associated with depletion of glucose and ATP. ATP depletion may impair healing of pla...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ekstrand, Matias, Widell, Emma, Hammar, Anna, Akyürek, Levent M., Johansson, Martin, Fagerberg, Björn, Bergström, Göran, Levin, Malin C., Fogelstrand, Per, Borén, Jan, Levin, Max
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453577/
https://ncbi.nlm.nih.gov/pubmed/28570702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178877
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