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Depletion of ATP and glucose in advanced human atherosclerotic plaques

OBJECTIVE: Severe hypoxia develops close to the necrotic core of advanced human atherosclerotic plaques, but the energy metabolic consequences of this hypoxia are not known. In animal models, plaque hypoxia is also associated with depletion of glucose and ATP. ATP depletion may impair healing of pla...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Ekstrand, Matias, Widell, Emma, Hammar, Anna, Akyürek, Levent M., Johansson, Martin, Fagerberg, Björn, Bergström, Göran, Levin, Malin C., Fogelstrand, Per, Borén, Jan, Levin, Max
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453577/
https://ncbi.nlm.nih.gov/pubmed/28570702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178877
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