Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene

The genomes of RNA and small DNA viruses of vertebrates display significant suppression of CpG dinucleotide frequencies. Artificially increasing dinucleotide frequencies results in substantial attenuation of virus replication, suggesting that these compositional changes may facilitate recognition of...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Lin, Yao-Tang, Chiweshe, Stephen, McCormick, Dominique, Raper, Anna, Wickenhagen, Arthur, DeFillipis, Victor, Gaunt, Eleanor, Simmonds, Peter, Wilson, Sam J., Grey, Finn
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498042/
https://ncbi.nlm.nih.gov/pubmed/32886716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008844
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