Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene

The genomes of RNA and small DNA viruses of vertebrates display significant suppression of CpG dinucleotide frequencies. Artificially increasing dinucleotide frequencies results in substantial attenuation of virus replication, suggesting that these compositional changes may facilitate recognition of...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Lin, Yao-Tang, Chiweshe, Stephen, McCormick, Dominique, Raper, Anna, Wickenhagen, Arthur, DeFillipis, Victor, Gaunt, Eleanor, Simmonds, Peter, Wilson, Sam J., Grey, Finn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498042/
https://ncbi.nlm.nih.gov/pubmed/32886716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008844
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