Porphyromonas gingivalis promotes progression of esophageal squamous cell cancer via TGFβ-dependent Smad/YAP/TAZ signaling

Microbial dysbiosis in the upper digestive tract is linked to an increased risk of esophageal squamous cell carcinoma (ESCC). Overabundance of Porphyromonas gingivalis is associated with shorter survival of ESCC patients. We investigated the molecular mechanisms driving aggressive progression of ESC...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Qi, Yi-Jun, Jiao, Ye-Lin, Chen, Pan, Kong, Jin-Yu, Gu, Bian-Li, Liu, Ke, Feng, Dan-Dan, Zhu, Ya-Fei, Ruan, Hao-Jie, Lan, Zi-Jun, Liu, Qi-Wei, Mi, You-Jia, Guo, Xiang-Qian, Wang, Ming, Liang, Gao-Feng, Lamont, Richard J., Wang, Huizhi, Zhou, Fu-You, Feng, Xiao-Shan, Gao, She-Gan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498034/
https://ncbi.nlm.nih.gov/pubmed/32886690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000825
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