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The proportion of endometrial tumours associated with Lynch syndrome (PETALS): A prospective cross-sectional study

BACKGROUND: Lynch syndrome (LS) predisposes to endometrial cancer (EC), colorectal cancer, and other cancers through inherited pathogenic variants affecting mismatch-repair (MMR) genes. Diagnosing LS in women with EC can reduce subsequent cancer mortality through colonoscopic surveillance and aspiri...

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Dades bibliogràfiques
Publicat a:PLoS Med
Autors principals: Ryan, Neil A. J., McMahon, Raymond, Tobi, Simon, Snowsill, Tristan, Esquibel, Shona, Wallace, Andrew J., Bunstone, Sancha, Bowers, Naomi, Mosneag, Ioana E., Kitson, Sarah J., O’Flynn, Helena, Ramchander, Neal C., Sivalingam, Vanitha N., Frayling, Ian M., Bolton, James, McVey, Rhona J., Evans, D. Gareth, Crosbie, Emma J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497985/
https://ncbi.nlm.nih.gov/pubmed/32941469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1003263
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