Targeting DNA Methylation Depletes Uterine Leiomyoma Stem Cell–enriched Population by Stimulating Their Differentiation

Uterine leiomyoma (LM) is the most common tumor in women and can cause severe morbidity. Leiomyoma growth requires the maintenance and proliferation of a stem cell population. Dysregulated deoxyribonucleic acid (DNA) methylation has been reported in LM, but its role in LM stem cell regulation remain...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Liu, Shimeng, Yin, Ping, Xu, Jingting, Dotts, Ariel J, Kujawa, Stacy A, Coon V, John S, Zhao, Hong, Shilatifard, Ali, Dai, Yang, Bulun, Serdar E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497820/
https://ncbi.nlm.nih.gov/pubmed/32812024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa143
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi