Targeting DNA Methylation Depletes Uterine Leiomyoma Stem Cell–enriched Population by Stimulating Their Differentiation

Uterine leiomyoma (LM) is the most common tumor in women and can cause severe morbidity. Leiomyoma growth requires the maintenance and proliferation of a stem cell population. Dysregulated deoxyribonucleic acid (DNA) methylation has been reported in LM, but its role in LM stem cell regulation remain...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Liu, Shimeng, Yin, Ping, Xu, Jingting, Dotts, Ariel J, Kujawa, Stacy A, Coon V, John S, Zhao, Hong, Shilatifard, Ali, Dai, Yang, Bulun, Serdar E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497820/
https://ncbi.nlm.nih.gov/pubmed/32812024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa143
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