Cargando...

Progesterone receptor integrates the effects of mutated MED12 and altered DNA methylation to stimulate RANKL expression and stem cell proliferation in uterine leiomyoma

Progesterone and its receptor, PR, are essential for uterine leiomyoma (LM, a.k.a., fibroid) tumorigenesis, but the underlying cellular and molecular mechanisms remain unclear. The receptor activator of NF-κB (RANKL) was recently identified as a novel progesterone/PR-responsive gene that plays an im...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Oncogene
Autores principales: Liu, Shimeng, Yin, Ping, Kujawa, Stacy A., Coon, John S., Okeigwe, Ijeoma, Bulun, Serdar E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461478/
https://ncbi.nlm.nih.gov/pubmed/30538295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0612-6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!