Structure-based design, synthesis, and evaluation of the biological activity of novel phosphoroorganic small molecule IAP antagonists

One of the strategies employed by novel anticancer therapies is to put the process of apoptosis back on track by blocking the interaction between inhibitor of apoptosis proteins (IAPs) and caspases. The activity of caspases is modulated by the caspases themselves in a caspase/procaspase proteolytic...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Invest New Drugs
Egile Nagusiak: Łupicka-Słowik, Agnieszka, Psurski, Mateusz, Grzywa, Renata, Cuprych, Monika, Ciekot, Jarosław, Goldeman, Waldemar, Wojaczyńska, Elżbieta, Wojaczyński, Jacek, Oleksyszyn, Józef, Sieńczyk, Marcin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer US 2020
Gaiak:
Preclinical Studies
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497679/
https://ncbi.nlm.nih.gov/pubmed/32270379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-020-00923-4
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