Maternal low-dose aspartame and stevia consumption with an obesogenic diet alters metabolism, gut microbiota and mesolimbic reward system in rat dams and their offspring

OBJECTIVE: We examined the impact of maternal low-dose aspartame and stevia consumption on adiposity, glucose tolerance, gut microbiota and mesolimbic pathway in obese dams and their offspring. DESIGN: Following obesity induction, female Sprague-Dawley rats were allocated during pregnancy and lactat...

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Veröffentlicht in:Gut
Hauptverfasser: Nettleton, Jodi E, Cho, Nicole A, Klancic, Teja, Nicolucci, Alissa C, Shearer, Jane, Borgland, Stephanie L, Johnston, Leah A, Ramay, Hena R, Noye Tuplin, Erin, Chleilat, Faye, Thomson, Carolyn, Mayengbam, Shyamchand, McCoy, Kathy D, Reimer, Raylene A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Gut Microbiota
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497576/
https://ncbi.nlm.nih.gov/pubmed/31996393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2018-317505
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