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Expression and function of epithelial cell adhesion molecule EpCAM: where are we after 40 years?

EpCAM (epithelial cell adhesion molecule) was discovered four decades ago as a tumor antigen on colorectal carcinomas. Owing to its frequent and high expression on carcinomas and their metastases, EpCAM serves as a prognostic marker, a therapeutic target, and an anchor molecule on circulating and di...

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Bibliografiske detaljer
Udgivet i:Cancer Metastasis Rev
Main Authors: Gires, Olivier, Pan, Min, Schinke, Henrik, Canis, Martin, Baeuerle, Patrick A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497325/
https://ncbi.nlm.nih.gov/pubmed/32507912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09898-3
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