Anticancer potential of some imidazole and fused imidazole derivatives: exploring the mechanism via epidermal growth factor receptor (EGFR) inhibition

Imidazole-based epidermal growth factor receptor (EGFR) inhibitors were computationally designed and synthesized. All the compounds were assessed for their anti-proliferative activity against five cancer cell lines, viz., MDA-MB-231 (breast), T47D (breast) and MCF-7 (breast), A549 (lung) and HT-29 (...

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Dades bibliogràfiques
Publicat a:RSC Med Chem
Autors principals: Kalra, Sourav, Joshi, Gaurav, Kumar, Manvendra, Arora, Sahil, Kaur, Harsimrat, Singh, Sandeep, Munshi, Anjana, Kumar, Raj
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2020
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497068/
https://ncbi.nlm.nih.gov/pubmed/33479688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00146e
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