Novel Anticancer Fused Pyrazole Derivatives as EGFR and VEGFR-2 Dual TK Inhibitors

EGFR and VEGFR-2 represent promising targets for cancer treatment as they are very important in tumor development as well as in angiogenesis and metastasis. In this work, 6-amino-4-(2-bromophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile 1 and (E)-4-(2-Bromobenzylidene)-5-methyl-2,4-...

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Bibliographische Detailangaben
Veröffentlicht in:Front Chem
Hauptverfasser: Saleh, Nashwa M., El-Gazzar, Marwa G., Aly, Hala M., Othman, Rana A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993756/
https://ncbi.nlm.nih.gov/pubmed/32039146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00917
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