Interaction of FGF9 with FGFR3‐IIIb/IIIc, a putative driver of growth and aggressive behaviour of hepatocellular carcinoma

BACKGROUND & AIMS: Recently, overexpression of the fibroblast growth factor receptor 3 (FGFR3) splice variants FGFR3‐IIIb and FGFR3‐IIIc was found in ~50% of hepatocellular carcinoma (HCC). Here, we aim to identify FGFR3‐IIIb/IIIc ligands, which drive the progression of HCC. METHODS: FACS, MTT a...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Liver Int
Autori principali: Paur, Jakob, Valler, Maximilian, Sienel, Rebecca, Taxauer, Karin, Holzmann, Klaus, Marian, Brigitte, Unterberger, Andreas, Mohr, Thomas, Berger, Walter, Gvozdenovich, Andja, Schimming, Johannes, Grusch, Michael, Grasl‐Kraupp, Bettina
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Liver Cancer
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496895/
https://ncbi.nlm.nih.gov/pubmed/32378800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14505
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