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Biphasic Liquid Microjunction Extraction for Profiling Neuronal RNA Modifications by Liquid Chromatography–Tandem Mass Spectrometry

RNA modifications are emerging as critical players in the spatiotemporal regulation of gene expression. Although liquid chromatography–tandem mass spectrometry (LC–MS/MS) enables the simultaneous quantification of numerous enzymatically modified RNAs in a biological sample, conventional RNA extracti...

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發表在:Anal Chem
Main Authors: Clark, Kevin D., Philip, Marina C., Tan, Yanqi, Sweedler, Jonathan V.
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496823/
https://ncbi.nlm.nih.gov/pubmed/32786436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c02830
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