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Sequence mapping of transfer RNA chemical modifications by liquid chromatography tandem mass spectrometry
Mass spectrometry is a powerful analytical tool for identifying and characterizing structural modifications to the four canonical bases in RNA, information that is lost when using techniques such as PCR for RNA analysis. Here we described an updated method for sequence mapping of modified nucleoside...
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Vydáno v: | Methods |
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Hlavní autoři: | , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
2016
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014671/ https://ncbi.nlm.nih.gov/pubmed/27033178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.03.016 |
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