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USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating the Wnt/β‐catenin pathway via Axin1 deubiquitination

Colorectal cancer (CRC) is the leading cause of cancer death, and its 5‐year survival rate remains unsatisfactory. Recent studies have revealed that ubiquitin‐specific protease 44 (USP44) is a cancer suppressor or oncogene depending on the type of neoplasm. However, its role in CRC remains unclear....

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Detalhes bibliográficos
Publicado no:Cell Biol Int
Main Authors: Huang, Tong, Zhang, Qingquan, Ren, Wei, Yan, Bing, Yi, Liang, Tang, Tielun, Lin, Hai, Zhang, Yongjiu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496820/
https://ncbi.nlm.nih.gov/pubmed/32285989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbin.11358
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