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Gasdermin D‐independent release of interleukin‐1β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides

Interleukin‐1β (IL‐1β) plays pivotal roles in controlling bacterial infections and is produced after the processing of pro‐IL‐1β by caspase‐1, which is activated by the inflammasome. In addition, caspase‐1 cleaves the cytosolic protein, gasdermin‐D (GSDMD), whose N‐terminal fragment subsequently for...

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Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Saeki, Ayumi, Tsuchiya, Kohsuke, Suda, Takashi, Into, Takeshi, Hasebe, Akira, Suzuki, Toshihiko, Shibata, Ken‐ichiro
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496788/
https://ncbi.nlm.nih.gov/pubmed/32592165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13230
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