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Gasdermin D‐independent release of interleukin‐1β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides
Interleukin‐1β (IL‐1β) plays pivotal roles in controlling bacterial infections and is produced after the processing of pro‐IL‐1β by caspase‐1, which is activated by the inflammasome. In addition, caspase‐1 cleaves the cytosolic protein, gasdermin‐D (GSDMD), whose N‐terminal fragment subsequently for...
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| Udgivet i: | Immunology |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7496788/ https://ncbi.nlm.nih.gov/pubmed/32592165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13230 |
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