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Impact of early pandemic stage mutations on molecular dynamics of SARS-CoV-2 M(pro)

The new coronavirus (SARS-CoV-2) is a global threat to the world health and economy. Its dimeric main protease (M(pro)), which is required for the proteolytic cleavage of viral precursor proteins, is a good candidate for drug development owing to its conservation and the absence of a human homolog....

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Dades bibliogràfiques
Publicat a:J Chem Inf Model
Autors principals: Amamuddy, Olivier Sheik, Verkhivker, Gennady M., Bishop, Özlem Tastan
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496595/
https://ncbi.nlm.nih.gov/pubmed/32853525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c00634
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