Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids

The archazolids are potent antiproliferative compounds that have recently emerged as a novel class of promising anticancer agents. Their complex macrolide structures and scarce natural supply make the development of more readily available analogues highly important. Herein, we report the design, syn...

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Publicado en:ChemMedChem
Autores principales: Rivière, Solenne, Vielmuth, Christin, Ennenbach, Christiane, Abdelrahman, Aliaa, Lemke, Carina, Gütschow, Michael, Müller, Christa E., Menche, Dirk
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496434/
https://ncbi.nlm.nih.gov/pubmed/32363789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000154
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