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Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages

Derivatives of 4‐aminomethyl‐l‐phenylalanine with aromatic oligoamide foldamers as sidechain appendages were successfully charged on tRNA by means of flexizymes. Their subsequent incorporation both at the C‐terminus of, and within, peptide sequences by the ribosome, was demonstrated. These results e...

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Bibliografiska uppgifter
I publikationen:Angew Chem Int Ed Engl
Huvudupphovsmän: Tsiamantas, Christos, Kwon, Sunbum, Rogers, Joseph M., Douat, Céline, Huc, Ivan, Suga, Hiroaki
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496375/
https://ncbi.nlm.nih.gov/pubmed/31894626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201914654
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