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Investigating the impact of alpha/beta and LET(d) on relative biological effectiveness in scanned proton beams: An in vitro study based on human cell lines

PURPOSE: A relative biological effectiveness (RBE) of 1.1 is commonly used in clinical proton therapy, irrespective of tissue type and depth. This in vitro study was conducted to quantify the RBE of scanned protons as a function of the dose‐averaged linear energy transfer (LET(d)) and the sensitivit...

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Dettagli Bibliografici
Pubblicato in:Med Phys
Autori principali: Mara, Elisabeth, Clausen, Monika, Khachonkham, Suphalak, Deycmar, Simon, Pessy, Clara, Dörr, Wolfgang, Kuess, Peter, Georg, Dietmar, Gruber, Sylvia
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496287/
https://ncbi.nlm.nih.gov/pubmed/32347564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mp.14212
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