Investigating the impact of alpha/beta and LET(d) on relative biological effectiveness in scanned proton beams: An in vitro study based on human cell lines

PURPOSE: A relative biological effectiveness (RBE) of 1.1 is commonly used in clinical proton therapy, irrespective of tissue type and depth. This in vitro study was conducted to quantify the RBE of scanned protons as a function of the dose‐averaged linear energy transfer (LET(d)) and the sensitivit...

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Vydáno v:Med Phys
Hlavní autoři: Mara, Elisabeth, Clausen, Monika, Khachonkham, Suphalak, Deycmar, Simon, Pessy, Clara, Dörr, Wolfgang, Kuess, Peter, Georg, Dietmar, Gruber, Sylvia
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
BIOLOGICAL PHYSICS AND RESPONSE PREDICTION
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496287/
https://ncbi.nlm.nih.gov/pubmed/32347564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mp.14212
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