Light Dynamics of the Retinal‐Disease‐Relevant G90D Bovine Rhodopsin Mutant

The RHO gene encodes the G‐protein‐coupled receptor (GPCR) rhodopsin. Numerous mutations associated with impaired visual cycle have been reported; the G90D mutation leads to a constitutively active mutant form of rhodopsin that causes CSNB disease. We report on the structural investigation of the re...

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發表在:Angew Chem Int Ed Engl
Main Authors: Kubatova, Nina, Mao, Jiafei, Eckert, Carl Elias, Saxena, Krishna, Gande, Santosh L., Wachtveitl, Josef, Glaubitz, Clemens, Schwalbe, Harald
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496284/
https://ncbi.nlm.nih.gov/pubmed/32602600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202003671
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