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3DeFDR: statistical methods for identifying cell type-specific looping interactions in 5C and Hi-C data

An important unanswered question in chromatin biology is the extent to which long-range looping interactions change across developmental models, genetic perturbations, drug treatments, and disease states. Computational tools for rigorous assessment of cell type-specific loops across multiple biologi...

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Bibliografski detalji
Izdano u:Genome Biol
Glavni autori: Fernandez, Lindsey R., Gilgenast, Thomas G., Phillips-Cremins, Jennifer E.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496221/
https://ncbi.nlm.nih.gov/pubmed/32859248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02061-9
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