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Modeling and analysis of Hi-C data by HiSIF identifies characteristic promoter-distal loops
Current computational methods on Hi-C analysis focused on identifying Mb-size domains often failed to unveil the underlying functional and mechanistic relationship of chromatin structure and gene regulation. We developed a novel computational method HiSIF to identify genome-wide interacting loci. We...
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| Publicat a: | Genome Med |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7425017/ https://ncbi.nlm.nih.gov/pubmed/32787954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00769-8 |
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