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Prediction of hot spots in protein–DNA binding interfaces based on supervised isometric feature mapping and extreme gradient boosting
BACKGROUND: Identification of hot spots in protein-DNA interfaces provides crucial information for the research on protein-DNA interaction and drug design. As experimental methods for determining hot spots are time-consuming, labor-intensive and expensive, there is a need for developing reliable com...
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| Publicado no: | BMC Bioinformatics |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7495874/ https://ncbi.nlm.nih.gov/pubmed/32938395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03683-3 |
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