IMPROvER: the Integral Membrane Protein Stability Selector

Identifying stabilising variants of membrane protein targets is often required for structure determination. Our new computational pipeline, the Integral Membrane Protein Stability Selector (IMPROvER) provides a rational approach to variant selection by employing three independent approaches: deep-se...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Harborne, Steven P. D., Strauss, Jannik, Boakes, Jessica C., Wright, Danielle L., Henderson, James G., Boivineau, Jacques, Jaakola, Veli-Pekka, Goldman, Adrian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495477/
https://ncbi.nlm.nih.gov/pubmed/32938971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71744-x
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