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IMPROvER: the Integral Membrane Protein Stability Selector

Identifying stabilising variants of membrane protein targets is often required for structure determination. Our new computational pipeline, the Integral Membrane Protein Stability Selector (IMPROvER) provides a rational approach to variant selection by employing three independent approaches: deep-se...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Harborne, Steven P. D., Strauss, Jannik, Boakes, Jessica C., Wright, Danielle L., Henderson, James G., Boivineau, Jacques, Jaakola, Veli-Pekka, Goldman, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495477/
https://ncbi.nlm.nih.gov/pubmed/32938971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71744-x
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