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Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion

Merkel cell polyomavirus (MCV) small T antigen (sT) is the main oncoprotein for the development of Merkel cell carcinoma (MCC). MCC is a rare, clinically aggressive neuroendocrine tumor of the skin with a high propensity for local, regional, and distant spread. The dysregulation of matrix metallopro...

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Pubblicato in:J Virol
Autori principali: Nwogu, Nnenna, Ortiz, Luz E., Whitehouse, Adrian, Kwun, Hyun Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495391/
https://ncbi.nlm.nih.gov/pubmed/32669331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00786-20
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