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A Stronger Transcription Regulatory Circuit of HIV-1C Drives the Rapid Establishment of Latency with Implications for the Direct Involvement of Tat

The magnitude of transcription factor binding site variation emerging in HIV-1 subtype C (HIV-1C), especially the addition of NF-κB motifs by sequence duplication, makes the examination of transcriptional silence challenging. How can HIV-1 establish and maintain latency despite having a strong long...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chakraborty, Sutanuka, Kabi, Manisha, Ranga, Udaykumar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495361/
https://ncbi.nlm.nih.gov/pubmed/32669338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00503-20
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