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RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges

RNA-based therapies, including RNA molecules as drugs and RNA-targeted small molecules, offer unique opportunities to expand the range of therapeutic targets. Various forms of RNAs may be used to selectively act on proteins, transcripts, and genes that cannot be targeted by conventional small molecu...

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Pubblicato in:Pharmacol Rev
Autori principali: Yu, Ai-Ming, Choi, Young Hee, Tu, Mei-Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495341/
https://ncbi.nlm.nih.gov/pubmed/32929000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.120.019554
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