Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy

Intratumor spatial heterogeneity facilitates therapeutic resistance in glioblastoma (GBM). Nonetheless, understanding of GBM heterogeneity is largely limited to the surgically resectable tumor core lesion while the seeds for recurrence reside in the unresectable tumor edge. In this study, stratifica...

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Argitaratua izan da:Nat Commun
Egile Nagusiak: Bastola, Soniya, Pavlyukov, Marat S., Yamashita, Daisuke, Ghosh, Sadashib, Cho, Heejin, Kagaya, Noritaka, Zhang, Zhuo, Minata, Mutsuko, Lee, Yeri, Sadahiro, Hirokazu, Yamaguchi, Shinobu, Komarova, Svetlana, Yang, Eddy, Markert, James, Nabors, Louis B., Bhat, Krishna, Lee, James, Chen, Qin, Crossman, David K., Shin-Ya, Kazuo, Nam, Do-Hyun, Nakano, Ichiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
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Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494913/
https://ncbi.nlm.nih.gov/pubmed/32938908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18189-y
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