Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart

Intercalated discs (ICD), specific cell-to-cell contacts that connect adjacent cardiomyocytes, ensure mechanical and electrochemical coupling during contraction of the heart. Mutations in genes encoding ICD components are linked to cardiovascular diseases. Here, we show that loss of Xinβ, a newly-id...

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Publicado no:Nat Commun
Main Authors: Guo, Haipeng, Lu, Yao Wei, Lin, Zhiqiang, Huang, Zhan-Peng, Liu, Jianming, Wang, Yi, Seok, Hee Young, Hu, Xiaoyun, Ma, Qing, Li, Kathryn, Kyselovic, Jan, Wang, Qingchuan, Lin, Jenny L.-C., Lin, Jim J.-C., Cowan, Douglas B., Naya, Francisco, Chen, Yuguo, Pu, William T., Wang, Da-Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494909/
https://ncbi.nlm.nih.gov/pubmed/32938943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18379-8
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