Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)

Emergence of tigecycline-resistance tet(X) gene orthologues rendered tigecycline ineffective as last-resort antibiotic. To understand the potential origin and transmission mechanisms of these genes, we survey the prevalence of tet(X) and its orthologues in 2997 clinical E. coli and K. pneumoniae iso...

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Publicado en:Nat Commun
Autores principales: Zhang, Rong, Dong, Ning, Shen, Zhangqi, Zeng, Yu, Lu, Jiauyue, Liu, Congcong, Zhou, Hongwei, Hu, Yanyan, Sun, Qiaoling, Cheng, Qipeng, Shu, Lingbing, Cai, Jiachang, Chan, Edward Wai-Chi, Chen, Gongxiang, Chen, Sheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494873/
https://ncbi.nlm.nih.gov/pubmed/32938927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18475-9
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