Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X)

Emergence of tigecycline-resistance tet(X) gene orthologues rendered tigecycline ineffective as last-resort antibiotic. To understand the potential origin and transmission mechanisms of these genes, we survey the prevalence of tet(X) and its orthologues in 2997 clinical E. coli and K. pneumoniae iso...

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Опубликовано в: :Nat Commun
Главные авторы: Zhang, Rong, Dong, Ning, Shen, Zhangqi, Zeng, Yu, Lu, Jiauyue, Liu, Congcong, Zhou, Hongwei, Hu, Yanyan, Sun, Qiaoling, Cheng, Qipeng, Shu, Lingbing, Cai, Jiachang, Chan, Edward Wai-Chi, Chen, Gongxiang, Chen, Sheng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494873/
https://ncbi.nlm.nih.gov/pubmed/32938927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18475-9
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