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YES1 amplification confers trastuzumab–emtansine (T-DM1) resistance in HER2-positive cancer
BACKGROUND: Trastuzumab–emtansine (T-DM1), one of the most potent HER2-targeted drugs, shows impressive efficacy in patients with HER2-positive breast cancers. However, resistance inevitably occurs and becomes a critical clinical problem. METHODS: We modelled the development of acquired resistance b...
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| Опубликовано в: : | Br J Cancer |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494777/ https://ncbi.nlm.nih.gov/pubmed/32572172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0952-1 |
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