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STAT3 activation confers trastuzumab‐emtansine (T‐DM1) resistance in HER2‐positive breast cancer

Trastuzumab‐emtansine (T‐DM1) is an antibody‐drug conjugate that has been approved for the treatment of human epidermal growth factor receptor 2 (HER2)‐positive metastatic breast cancer. Despite the remarkable efficacy of T‐DM1 in many patients, resistance to this therapeutic has emerged as a signif...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Wang, Lei, Wang, Quanren, Gao, Mingzhao, Fu, Li, Li, Yun, Quan, Haitian, Lou, Liguang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172075/
https://ncbi.nlm.nih.gov/pubmed/30076657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13761
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