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Protein splicing activity of the Haloferax volcanii PolB-c intein is sensitive to homing endonuclease domain mutations

Inteins are selfish genetic elements residing in open reading frames that can splice post-translationally, resulting in the ligation of an uninterrupted, functional protein. Like other inteins, the DNA polymerase B (PolB) intein of the halophilic archaeon Haloferax volcanii has an active homing endo...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Robinzon, Shachar, Cawood, Alexandra R., Ruiz, Mercedes A., Gophna, Uri, Altman-Price, Neta, Mills, Kenneth V.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494616/
https://ncbi.nlm.nih.gov/pubmed/32822531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00512
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