NF-κB inhibitor, NEMO-binding domain peptide attenuates intervertebral disc degeneration

BACKGROUND CONTEXT: Non-physiological mechanical loading and inflammation are both critically involved in intervertebral disc (IVD) degeneration, which is characterized by an increase in cytokines and matrix metalloproteases (MMPs) in the nucleus pulposus (NP). This process is known to be mediated b...

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Détails bibliographiques
Publié dans:Spine J
Auteurs principaux: Glaeser, Juliane D., Salehi, Khosrowdad, Kanim, Linda E.A., NaPier, Zachary, Kropf, Michael A., Cuéllar, Jason M., Perry, Tiffany G., Bae, Hyun W., Sheyn, Dmitriy
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494571/
https://ncbi.nlm.nih.gov/pubmed/32413485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2020.04.025
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