NF-κB inhibitor, NEMO-binding domain peptide attenuates intervertebral disc degeneration

BACKGROUND CONTEXT: Non-physiological mechanical loading and inflammation are both critically involved in intervertebral disc (IVD) degeneration, which is characterized by an increase in cytokines and matrix metalloproteases (MMPs) in the nucleus pulposus (NP). This process is known to be mediated b...

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Publicat a:Spine J
Autors principals: Glaeser, Juliane D., Salehi, Khosrowdad, Kanim, Linda E.A., NaPier, Zachary, Kropf, Michael A., Cuéllar, Jason M., Perry, Tiffany G., Bae, Hyun W., Sheyn, Dmitriy
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494571/
https://ncbi.nlm.nih.gov/pubmed/32413485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2020.04.025
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