The NRF2/KEAP1 Pathway Modulates Nasopharyngeal Carcinoma Cell Radiosensitivity via ROS Elimination

PURPOSE: Radioresistance is a vital obstacle for the prognosis of human nasopharyngeal carcinoma (NPC), but the underlying mechanism is still unknown. Here, we explored the role of the NRF2/KEAP1 pathway in radioresistance of NPC cell lines. MATERIALS AND METHODS: We selected NPC cell lines CNE-1 an...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Zhou, Jieyu, Ding, Jiping, Ma, Xingkai, Zhang, Meichao, Huo, Zirong, Yao, Yuan, Li, Dong, Wang, Zhentao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494231/
https://ncbi.nlm.nih.gov/pubmed/32982300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S260169
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