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Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway
Nrf2 is the major transcription factor that regulates many of the cytoprotective enzymes involved in the adaptive stress response. Modulation of Nrf2 could be therapeutically useful in a number of disease states. Activation can occur through either an electrophilic or non-electrophilic mechanism. To...
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| Publicado en: | Bioorg Med Chem Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643947/ https://ncbi.nlm.nih.gov/pubmed/25937010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.04.019 |
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