Oridonin Sensitizes Hepatocellular Carcinoma to the Anticancer Effect of Sorafenib by Targeting the Akt Pathway

BACKGROUND: Oridonin is the core bioactive component of Rabdosia rubescens, a traditional Chinese herbal medicine used in the treatment of hepatoma. Sorafenib, a targeted therapeutic agent for advanced hepatocellular carcinoma (HCC), has recently been shown to exert limited clinical effects. However...

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Publicat a:Cancer Manag Res
Autors principals: Li, Xuguang, Chen, Weirun, Liu, Kaihang, Zhang, Sheng, Yang, Ru, Liu, Kairui, Li, Dateng, Huang, Youxing
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494228/
https://ncbi.nlm.nih.gov/pubmed/32982405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S257482
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