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Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration

Zebrafish regenerate heart muscle through division of pre-existing cardiomyocytes. To discover underlying regulation, we assess transcriptome datasets for dynamic gene networks during heart regeneration and identify suppression of genes associated with the transcription factor Tp53. Cardiac damage l...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Shoffner, Adam, Cigliola, Valentina, Lee, Nutishia, Ou, Jianhong, Poss, Kenneth D.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494019/
https://ncbi.nlm.nih.gov/pubmed/32877671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108089
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