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Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration

Zebrafish regenerate heart muscle through division of pre-existing cardiomyocytes. To discover underlying regulation, we assess transcriptome datasets for dynamic gene networks during heart regeneration and identify suppression of genes associated with the transcription factor Tp53. Cardiac damage l...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Shoffner, Adam, Cigliola, Valentina, Lee, Nutishia, Ou, Jianhong, Poss, Kenneth D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494019/
https://ncbi.nlm.nih.gov/pubmed/32877671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108089
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